122702-20-9

Basic information

• Product Name: D-serinaMide hydrochloride
• Synonyms: D-serinaMide hydrochloride;D(+)-serineamidehydrochloride;(R)-2-Amino-3-hydroxypropanamide hydrochloride;D-seriMide hydrochloride;D-Serinamide Hydrochloride(WX665005)
• CAS NO: 122702-20-9
• Molecular Formula: C₃H₈N₂O₂*ClH
• Molecular Weight: 140.56876
• EINECS: -0
• Mol File: 122702-20-9.mol
• Article Data: 2

Chemical Properties

• Melting Point: 188-189 °C
• Appearance: /
• Storage Temp.: Inert atmosphere,Room Temperature
• CAS DataBase Reference: D-serinaMide hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: D-serinaMide hydrochloride(122702-20-9)
• EPA Substance Registry System: D-serinaMide hydrochloride(122702-20-9)

Safety Data

• Hazardous Substances Data: 122702-20-9(Hazardous Substances Data)

Usage

General Description

D-serine is an amino acid that acts as a neurotransmitter in the central nervous system, and D-serine hydrochloride is the hydrochloride salt form of this compound. It is commonly used in scientific research as a tool to study the role of D-serine in neurotransmission and synaptic plasticity. D-serine is thought to play a key role in conditions such as schizophrenia and Alzheimer's disease, and its hydrochloride form allows for easier handling and storage in laboratory settings. This chemical is often used in the preparation of experimental solutions and as a reference standard for analytical testing. It is important to handle D-serine hydrochloride with care, as it can be harmful if ingested or inhaled, and should be stored in a cool, dry place away from heat and light.

Upstream product

• 80312-69-2 tert-butyl (R)-(1-amino-3-hydroxy-1-oxopropan-2-yl)carbamate 

Downstream Products

• 116833-21-7 (R)-2-dimethylamino-3-hydroxypropionamide 
• 1436421-67-8 (R)-4-((1-amino-3-hydroxy-1-oxopropan-2-ylamino)methyl)-N-(4-chloro-2-(4-(3,3,3-trifluoropropyl)piperazin-1-yl)phenyl)-2-fluorobenzamide hydrochloride 
• 1436422-13-7 (R)-4-((1-amino-3-hydroxy-1-oxopropan-2-ylamino)methyl)-N-(4-chloro-2-(4-(3,3,3-trifluoropropyl)piperazin-1-yl)phenyl)-2,3-difluorobenzamide 
• 556-02-5 ?Tyr 

Relevant articles and documents

MODULATORS OF THE G PROTEIN-COUPLED MAS RECEPTOR AND THE TREATMENT OF DISORDERS RELATED THERETO

The present invention relates to compounds of Formula (I) and pharmaceutically acceptable salts, solvates, and hydrates thereof that are useful in methods of treatment and alleviation of diseases and disorders of the heart, brain, kidney, immune, and reproductive system resulting from ischemia, or reperfusion subsequent to ischemia, and any downstream complication(s) related thereto. The present invention further relates to methods of treatment and alleviation of diseases and disorders of the vasculature resulting from vasoconstriction or hypertension and any downstream complication(s) resulting from elevated blood pressure and/or reduced tissue perfusion.