122706-84-7Relevant academic research and scientific papers
APOPTOTIC AND ANTI-TUMOR ACTIVITIES OF METALLO-SALENS
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Page/Page column 5, (2010/01/31)
The present invention describes the synthesis and biochemical activities of metallo-salen compounds and their derivatives. The Mn(III)-salen and Fe(III)-salen derivatives of the present invention are potential anti-tumor agents, that affect cell viability, induce strong apoptotic activity, cause nuclear condensation, fragmentation, and ultimately death in breast cancer cells MCF-7.
