1227083-35-3Relevant academic research and scientific papers
Amines bearing tertiary substituents by tandem enantioselective carbolithiation-rearrangement of vinylureas
Tait, Michael,Donnard, Morgan,Minassi, Alberto,Lefranc, Julien,Bechi, Beatrice,Carbone, Giorgio,O'Brien, Peter,Clayden, Jonathan
supporting information, p. 34 - 37 (2013/03/28)
In the presence of (-)-sparteine or a (+)-sparteine surrogate, organolithiums add to N-alkenyl-N'-arylureas to give benzylic organolithiums in an enantioselective manner. Under the influence of DMPU, these organolithiums undergo rearrangement with migrati
Geometry-selective synthesis of e or Z N -vinyl ureas (N -carbamoyl enamines)
Lefranc, Julien,Tetlow, Daniel J.,Donnard, Morgan,Minassi, Alberto,Galvez, Erik,Clayden, Jonathan
supporting information; experimental part, p. 296 - 299 (2011/03/22)
N-Vinyl ureas are emerging as a valuable class of compounds with both nucleophilic and electrophilic reactivity. They may be made by capturing the enamine tautomer of an imine with an isocyanate, a reaction which in general leads to the E isomer of the vi
Tandem β-alkylation-α-arylation of amines by carbolithiation and rearrangement of N -carbamoyl enamines (Vinyl Ureas)
Clayden, Jonathan,Donnard, Morgan,Lefranc, Julien,Minassi, Alberto,Tetlow, Daniel J.
supporting information; experimental part, p. 6624 - 6625 (2010/07/03)
Organolithiums add in an umpolung fashion to the β-carbon of N-carbamoyl enamines (N-vinyl ureas). The reaction proceeds with syn diastereospecificity and provides urea-stabilized, configurationally defined organolithiums. Facilitated by coordinating solv
