1227095-92-2Relevant academic research and scientific papers
Preparation of modified peptides: Direct conversion of α-amino acids into β-amino aldehydes
Saavedra, Carlos J.,Boto, Alicia,Hernandez, Rosendo
experimental part, p. 4448 - 4461 (2012/07/14)
A direct method for the transformation of α-amino acids into β-amino aldehydes was developed, and applied to the modification of the C-terminal residue of peptides. The method takes place in good yields and under mild conditions. The application of this methodology to the preparation of small peptides with γ-amino alcohol units, which are precursors of analogues of peptaibol antibiotics, is also described.
One-pot conversion of α-amino acids into β-amino aldehydes or 2-acetoxyazetidines: Application to the synthesis of modified peptides
Boto, Alicia,Hernández, Rosendo,Saavedra, Carlos J.
experimental part, p. 659 - 663 (2010/09/18)
A direct method for the transformation of α-amino acids into β-amino aldehydes or 2-acetoxyazetidines is described. This work was applied to the modification of peptides. Georg Thieme Verlag Stuttgart.
