1227154-44-0Relevant articles and documents
Low molecular weight dual inhibitors of factor Xa and fibrinogen binding to GPIIb/IIIa with highly overlapped pharmacophores
Trstenjak, Uro?,Ila?, Janez,Kikelj, Danijel
, p. 302 - 313 (2013)
Dual antithrombotic agents acting as anticoagulants and aggregation inhibitors could have substantial advantages over currently prescribed combinations of antithrombotic drugs. Herein, we report compounds with moderate inhibitory activity for factor Xa an
Design and synthesis of boron containing potential pan-RAR inverse agonists
Das, Bhaskar C.,Tang, Xiang-Ying,Evans, Todd
body text, p. 1316 - 1318 (2012/04/04)
We designed and successfully synthesized the compounds 5 and 8 as potential pan-RAR (retinoic acid receptor) agonists. These two compounds were designed based on an existing pan-RAR agonist (BMS493). We synthesized compound 5, in which the carboxylic acid