1227180-58-6

Basic information

• Product Name: 3-(2,4,6-trimethyl)phenyl-4-(methoxy)-1,2-benzisoxazole
• Synonyms: 3-(2,4,6-trimethyl)phenyl-4-(methoxy)-1,2-benzisoxazole
• CAS NO: 1227180-58-6
• Molecular Weight: 267.327
• Mol File: 1227180-58-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-(2,4,6-trimethyl)phenyl-4-(methoxy)-1,2-benzisoxazole(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2,4,6-trimethyl)phenyl-4-(methoxy)-1,2-benzisoxazole(1227180-58-6)
• EPA Substance Registry System: 3-(2,4,6-trimethyl)phenyl-4-(methoxy)-1,2-benzisoxazole(1227180-58-6)

Safety Data

• Hazardous Substances Data: 1227180-58-6(Hazardous Substances Data)

Upstream product

• 2904-57-6 mesitylenecarbonitrile oxide 
• 881009-83-2 2-methoxy-6-(trimethylsilyl)phenyltrifluoromethanesulfonate 

Relevant articles and documents

Trifluoromethanesulfonyloxy-group-directed regioselective (3 + 2) cycloadditions of benzynes for the synthesis of functionalized benzo-fused heterocycles

Highly regioselective (3 + 2) cycloadditions of (trifluoromethanesulfonyloxy)benzynes [(triflyloxy)benzynes] with 1,3-dipoles followed by cross-coupling reactions provided multisubstituted benzo-fused heterocycles. The triflyloxy group at the 3-position of benzynes, and even that at the remote 4-position, greatly affected the regiocontrol of the cycloaddition. These groups also served to install other substituents at their ipso-positions.