1227243-07-3

Upstream product

• 63503-60-6 3-chlorophenylboronic acid 
• 1227164-96-6 8-(3-chloro-phenyl)-2-methyl-imidazo[1,2-a]pyridine-6-carboxylic acid methyl ester 
• 1227164-98-8 [8-(3-chloro-phenyl)-2-methyl-imidazo[1,2-a]pyridin-6-yl]-methanol 
• 1227164-91-1 6-amino-5-(3-chloro-phenyl)-nicotinic acid methyl ester 
• 180340-70-9 methyl 6-amino-5-bromopyridine-3-carboxylate 
• 827614-64-2 2-aminopyridine-5-boronic acid pinacol ester 
• 1227165-17-4 carbonic acid 8-(3-chloro-phenyl)-2-methyl-imidazo[1,2-a]pyridin-6-ylmethyl ester methyl ester 

Downstream Products

• 1227243-17-5 C₂₆H₂₅ClN₄O₄ 
• 1227243-08-4 1-{5-[8-(3-chloro-phenyl)-2-methyl-imidazo[1,2-a]pyridin-6-ylmethyl]-pyridin-2-yl}-3-ethyl-urea 
• 1227243-16-4 N-{5-[8-(3-chloro-phenyl)-2-methyl-imidazo[1,2-a]pyridin-6-ylmethyl]-pyridin-2-yl}-2-dimethylamino-acetamide 
• 1227243-18-6 {5-[8-(3-chloro-phenyl)-2-methyl-imidazo[1,2-a]pyridin-6-ylmethyl]-pyridin-2-yl}-carbamic acid ethyl ester 

Relevant academic research and scientific papers

SUBSTITUTED AZA-BRIDGED BICYCLICS FOR CARDIOVASCULAR AND CNS DISEASE

The invention relates to substituted imidazopyridines, pyrazolotriazinones, triazolopyridines, pyrazolopyridines and pyrazolopyrimidines that are useful for treating stroke, myocardial infarct, and cardiovascular inflammatory conditions, to pharmaceutical compositions comprising these compounds, and to methods for the treatment of stroke, myocardial infarct, and cardiovascular inflammatory conditions in a mammal. The compounds have general formula I (I) or II (II) in which Cy1 and Cy2 are carbocycles or heterocycles.

PDE4 INHIBITORS SELECTIVE FOR THE LONG FORM OF PDE4 FOR TREATING INFLAMMATION AND AVOIDING SIDE EFFECTS

The present invention relates to compounds which are inhibitors of phosphodiesterase-4 (PDE4) useful for the treatment and prevention of stroke, myocardial infarct, cardiovascular inflammatory diseases and disorders and central nervous system disorders, t