1227270-38-3 Usage
General Description
Methyl 5-fluoro-1H-indazole-6-carboxylate is a chemical compound with the molecular formula C9H7FN2O2. It is a synthetic organic compound that belongs to the class of indazole derivatives. This chemical is typically used in the pharmaceutical industry as a building block in the synthesis of various pharmaceutical drugs. Its unique structure and properties make it useful for developing potential drug candidates or as an intermediate in the production of pharmaceuticals. Additionally, it may also have potential applications in other fields such as chemical research and material science. Overall, Methyl 5-fluoro-1H-indazole-6-carboxylate plays an important role in the development and production of various compounds with potential pharmaceutical and industrial applications.
Check Digit Verification of cas no
The CAS Registry Mumber 1227270-38-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,2,7,2,7 and 0 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1227270-38:
(9*1)+(8*2)+(7*2)+(6*7)+(5*2)+(4*7)+(3*0)+(2*3)+(1*8)=133
133 % 10 = 3
So 1227270-38-3 is a valid CAS Registry Number.
1227270-38-3Relevant articles and documents
Discovery of Indole- and Indazole-acylsulfonamides as Potent and Selective NaV1.7 Inhibitors for the Treatment of Pain
Luo, Guanglin,Chen, Ling,Easton, Amy,Newton, Amy,Bourin, Clotilde,Shields, Eric,Mosure, Kathy,Soars, Matthew G.,Knox, Ronald J.,Matchett, Michele,Pieschl, Rick L.,Post-Munson, Debra J.,Wang, Shuya,Herrington, James,Graef, John,Newberry, Kimberly,Sivarao, Digavalli V.,Senapati, Arun,Bristow, Linda J.,Meanwell, Nicholas A.,Thompson, Lorin A.,Dzierba, Carolyn
, p. 831 - 856 (2019/01/21)
3-Aryl-indole and 3-aryl-indazole derivatives were identified as potent and selective Nav1.7 inhibitors. Compound 29 was shown to be efficacious in the mouse formalin assay and also reduced complete Freund's adjuvant (CFA)-induced thermal hyper