1227270-58-7 Usage
General Description
1-(Phenylsulphonyl)-2,5-diMethyl-7-azaindole is a chemical compound with a molecular formula of C15H15NOS. It is a derivative of 7-azaindole, which is a heterocyclic compound with a nitrogen atom in the ring structure. The compound features a sulphonyl group attached to the phenyl ring and methyl groups at the 2 and 5 positions of the indole ring. It may have potential applications in medicinal chemistry and drug development due to its unique structure and potential biological activities. However, further research is needed to fully understand its properties and potential uses.
Check Digit Verification of cas no
The CAS Registry Mumber 1227270-58-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,2,7,2,7 and 0 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1227270-58:
(9*1)+(8*2)+(7*2)+(6*7)+(5*2)+(4*7)+(3*0)+(2*5)+(1*8)=137
137 % 10 = 7
So 1227270-58-7 is a valid CAS Registry Number.
1227270-58-7Relevant articles and documents
Discovery of Fevipiprant (NVP-QAW039), a Potent and Selective DP2 Receptor Antagonist for Treatment of Asthma
Sandham, David A.,Barker, Lucy,Brown, Lyndon,Brown, Zarin,Budd, David,Charlton, Steven J.,Chatterjee, Devnandan,Cox, Brian,Dubois, Gerald,Duggan, Nicholas,Hall, Edward,Hatto, Julia,Maas, Janet,Manini, Jodie,Profit, Rachael,Riddy, Darren,Ritchie, Catherine,Sohal, Bindi,Shaw, Duncan,Stringer, Rowan,Sykes, David A.,Thomas, Matthew,Turner, Katharine L.,Watson, Simon J.,West, Ryan,Willard, Elisabeth,Williams, Gareth,Willis, Jennifer
supporting information, p. 582 - 586 (2017/05/17)
Further optimization of an initial DP2 receptor antagonist clinical candidate NVP-QAV680 led to the discovery of a follow-up molecule 2-(2-methyl-1-(4-(methylsulfonyl)-2-(trifluoromethyl)benzyl)-1H-pyrrolo[2,3-b]pyridin-3-yl)acetic acid (compou
