1227296-12-9Relevant academic research and scientific papers
Photochemical synthesis of nucleoside analogues from cyclobutanones: Bicyclic and isonucleosides
Jaffer, Mileina,Ebead, Abdelaziz,Lee-Ruff, Edward
experimental part, p. 3816 - 3828 (2010/10/03)
The preparation of two nucleoside analogues are reported. Both syntheses involve a key photochemical ring-expansion of cyclobutanones to an oxacarbene and its subsequent scavenging by 6-chloropurine. The synthesis of a bicyclic (locked) purine starts from
