122734-26-3

Basic information

• Product Name: (2-Chloro-5-nitro-phenylamino)-oxo-dithioacetic acid; compound with triethyl-amine
• CAS NO: 122734-26-3
• Molecular Weight: 377.916
• Mol File: 122734-26-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2-Chloro-5-nitro-phenylamino)-oxo-dithioacetic acid; compound with triethyl-amine(CAS DataBase Reference)
• NIST Chemistry Reference: (2-Chloro-5-nitro-phenylamino)-oxo-dithioacetic acid; compound with triethyl-amine(122734-26-3)
• EPA Substance Registry System: (2-Chloro-5-nitro-phenylamino)-oxo-dithioacetic acid; compound with triethyl-amine(122734-26-3)

Safety Data

• Hazardous Substances Data: 122734-26-3(Hazardous Substances Data)

Upstream product

• 108086-37-9 2-chloro-N-(2-chloro-5-nitrophenyl)acetamide 
• 121-44-8 triethylamine 

Downstream Products

• 125983-18-8 (2-Chloro-5-nitro-phenylamino)-oxo-dithioacetic acid methyl ester 

Relevant articles and documents

Dithiocarboxylic Acids, Dithiocarboxylic Esters, or Thiocarboxylic Amides by Reaction of Methylene-active Chloromethyl Compounds with Sulfur

With a mixture of sulfur and amine in DMF at room temperature halomethyl compounds (1,5-10) can be oxidized to give thiocarboxylic acids (2,11-16) and their derivatives (3,4,17-35).We studied this reaction in detail especially with chloroacetic derivatives (11-15) or chloromethyl heterocycles (16) formally derived from chloroacetic acid.The resulting thiooxalic acid derivatives (11-27) represent activated acids and very useful C2-synthons, especially for the synthesis of heterocycles.Oxidation in the presence of triethylamine leads to dithiocarboxylates (11-16) which can be alkylated to dithioesters (17-27) in high yields.As a rule, with different primary and secondary amines instead of tertiary amines these dithiocarboxylates or dithiocarboxylic esters can be transformed already at low temperatures to thioamides (28-35).