1227380-90-6 Usage
General Description
EsoMeprazole related substance H431/41 is a chemical substance that is related to EsoMeprazole, a medication used to treat the symptoms of gastroesophageal reflux disease (GERD) and other conditions caused by excess stomach acid. This substance is considered a related impurity or byproduct that may be present in the production of EsoMeprazole. It is important to monitor and control the levels of this substance in pharmaceutical products to ensure the safety and effectiveness of the medication. Regulatory agencies and pharmaceutical companies closely monitor the presence of EsoMeprazole related substance H431/41 to ensure that it does not pose any risks to patients.
Check Digit Verification of cas no
The CAS Registry Mumber 1227380-90-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,2,7,3,8 and 0 respectively; the second part has 2 digits, 9 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1227380-90:
(9*1)+(8*2)+(7*2)+(6*7)+(5*3)+(4*8)+(3*0)+(2*9)+(1*0)=146
146 % 10 = 6
So 1227380-90-6 is a valid CAS Registry Number.
1227380-90-6Relevant articles and documents
Synthesis, characterization and molecular docking studies of acetamide derivatives of 2-aminothiazole and 2-dihydropyridinone derivative of benzimidazole
Anbazhagan, V.,Britto, S.,Kanagasabapathy, G.
, (2022/01/13)
An efficient and easy synthesis of highly functionalized thiazole and pyridinone-substituted benzimidazole derivatives has been developed. The imino carbon of the benzimidazole derivative is coupled with the nitrogen atom of 1,4-dihydropyridinone and the aminothiazole-substituted acetic acid is condensed with two differently functionalized aniline, in two different reactions to form the amide linkages. These two amides and pyridinone-coupled benzimidazole are characterized by IR, 1H & 13C NMR and mass spectral studies. They are further evaluated for their antibacterial activity against the gram-positive bacterium Staphylococcus epidermidis and the fungus Saccharomyces cerevisiae by molecular docking method. All the three synthesized compounds had relatively lesser binding energy than what the standard drugs chloramphenicol and fluconazole have and may be considered as better inhibitors.
