122743-45-7

Basic information

• Product Name: (3S,5R)-3-Benzyloxycarbonylmethyl-2-oxo-5-phenyl-morpholine-4-carboxylic acid tert-butyl ester
• CAS NO: 122743-45-7
• Molecular Weight: 425.481
• Mol File: 122743-45-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (3S,5R)-3-Benzyloxycarbonylmethyl-2-oxo-5-phenyl-morpholine-4-carboxylic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (3S,5R)-3-Benzyloxycarbonylmethyl-2-oxo-5-phenyl-morpholine-4-carboxylic acid tert-butyl ester(122743-45-7)
• EPA Substance Registry System: (3S,5R)-3-Benzyloxycarbonylmethyl-2-oxo-5-phenyl-morpholine-4-carboxylic acid tert-butyl ester(122743-45-7)

Safety Data

• Hazardous Substances Data: 122743-45-7(Hazardous Substances Data)

Upstream product

• 121269-45-2 (R)-5-phenyl-3,4,5,6-tetrahydro-2H-1,4-oxazin-2-one 
• 56613-80-0 D-2-phenylglycinol 
• 24424-99-5 di-tert-butyl dicarbonate 
• 119878-90-9 (5R)-4-(tert-butyloxycarbonyl)-5-phenyl-2,3,5,6-tetrahydro-4H-1,4-oxazin-2-one 
• 5437-45-6 Benzyl bromoacetate 

Relevant articles and documents

STEREOSELECTIVE ALKYLATION OF CHIRAL GLYCINE ENOLATE SYNTHONS. THE ENANTIOSELECTIVE SYNTHESIS O α-AMINO ACID DERIVATES

The highly stereoselective alkylation (percentde=99.6 to 97.6) o a new chiral glycine enolate synthon derived from D-2-phenylglycinol is described.Deprotection of the alkylation adducts in a one-pot, three-step procedure provides the ethyl ester hydrochloride salts of the corresponding α-amino acids with no attending racemization.