1227499-89-9

Basic information

• Product Name: 2-CHLORO-5-METHOXYPYRIDINE-3-ACETIC ACID
• Synonyms: 2-CHLORO-5-METHOXYPYRIDINE-3-ACETIC ACID;(2-Chloro-5-methoxy-pyridin-3-yl)acetic acid
• CAS NO: 1227499-89-9
• Molecular Formula: C8H8ClNO3
• Molecular Weight: 201.60702
• Mol File: 1227499-89-9.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 375.9±37.0 °C(Predicted)
• Appearance: /
• Density: 1.380±0.06 g/cm3(Predicted)
• PKA: 3.68±0.10(Predicted)
• CAS DataBase Reference: 2-CHLORO-5-METHOXYPYRIDINE-3-ACETIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CHLORO-5-METHOXYPYRIDINE-3-ACETIC ACID(1227499-89-9)
• EPA Substance Registry System: 2-CHLORO-5-METHOXYPYRIDINE-3-ACETIC ACID(1227499-89-9)

Safety Data

• Hazardous Substances Data: 1227499-89-9(Hazardous Substances Data)

Upstream product

• 1256791-15-7 methyl 2-chloro-5-methoxynicotinate 

Relevant articles and documents

TOPICAL FORMULATIONS

Provided herein are gelled topical formulations for the treatment of skin diseases comprising: a) a MEK inhibitor; b) one or more organic solvents in an amount of about 70% to about 99% by weight; and c) a gelling agent; wherein the one or more organic solvents are selected from the group consisting of C2-6 alcohol, a C2-6 alkylene glycol, a di-(C2-6 alkylene) glycol, a polyethylene glycol, C1-3 alkyl-(OCH2CH2)1-5-OH, DMSO, ethyl acetate, acetone, N-methyl pyrrolidone, benzyl alcohol, glycerin, and an oil; the gelling agent is hydroxypropyl cellulose having a molecular weight ranging from about 40,000 Dato about 2,500,000 Da; and wherein the gelled topical formulation has a viscosity of from 1 to 25,000 cps; and DMSO, when present, is combined with at least one other of said organic solvents such that DMSO is present in an amount of less than 50% by weight.

ARYL-ANILINE AND HETEROARYL-ANILINE COMPOUNDS FOR TREATMENT OF BIRTHMARKS

Provided herein are compounds and pharmaceutical compositions thereof for treating a birthmark in a subject in need thereof, wherein the compound is according to any one of formula (1), (II), (III), (IV), and (V). wherein X1, X2, X3, R1, R2, R2a, R13, R13a, R23, R23a, R23b, R33, R33a, R33b, R43, R43a, R51, R53, R53a, R53b, bond "a", and subscript n are described herein.