122751-80-8Relevant articles and documents
Isoxazole-β-carboline derivatives
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, (2008/06/13)
β-Carbolines of general Formula I STR1 wherein Y represents the residue STR2 and R a and R b, being identical or different, mean respectively hydrogen, C 1-6 -alkoxy, phenyl, C 3-7 -cyclo-alkyl, optionally substituted C 1-6 -alkyl or C 1-6 -alkoxycarbonyl, and R c and R d, being identical or different, mean respectively hydrogen or C 1-6 -alkyl or jointly a linkage, andR 4 is hydrogen, C 1-6 -alkyl or C 1-6 -alkoxy-C 1-6 -alkyl andR 5 is hydrogen, halogen, OR 6, NR 7 R 8 or CH R 9 R 10 wherein R 6 means C 1-6 -alkyl, C 3-7 -cycloalkyl or an optionally substituted aralkyl, aryl or hetaryl residue, R 7 and R 8, being identical or different, represent hydrogen, C 1-6 -alkyl, C 3-6 -alkenyl, or jointly with the nitrogen atom a saturated heterocyclic five- or six-membered ring which optionally contains a further hetero atom, R 9 means hydrogen or C 1-6 -alkyl, R 10 means hydrogen, C 1-6 -alkyl, OR 11 or NR 12 R 13 wherein R 11 means C 1-6 -alkyl, R 12 and R 13 are identical or different and mean hydrogen, C 1-6 -alkyl or jointly with the nitrogen atom a saturated heterocyclic five- or six-membered ring optionally containing a further hetero atom, are useful to treat epilepsy or anxiety.
