1227617-38-0

Basic information

• Product Name: tert-butyl 3-(3,4-difluorophenyl)-3-hydroxyazetidine-1-carboxylate
• Synonyms: tert-butyl 3-(3,4-difluorophenyl)-3-hydroxyazetidine-1-carboxylate
• CAS NO: 1227617-38-0
• Molecular Weight: 285.291
• Mol File: 1227617-38-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: tert-butyl 3-(3,4-difluorophenyl)-3-hydroxyazetidine-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 3-(3,4-difluorophenyl)-3-hydroxyazetidine-1-carboxylate(1227617-38-0)
• EPA Substance Registry System: tert-butyl 3-(3,4-difluorophenyl)-3-hydroxyazetidine-1-carboxylate(1227617-38-0)

Safety Data

• Hazardous Substances Data: 1227617-38-0(Hazardous Substances Data)

Upstream product

• 398489-26-4 tert-butyl 3-oxoazetidine-1-carboxylate 
• 348-61-8 1-bromo-3,4-difluorobenzene 

Downstream Products

• 1227617-05-1 3-(3,4-difluorophenyl)azetidin-3-ol 
• 1227617-03-9 3-(3,4-Difluorophenyl)-1-propylazetidin-3-ol 
• 1227617-12-0 3-(3,4-difluorophenyl)-1-(propyl-d7)azetidin-3-ol 

Relevant articles and documents

NOVEL 1-ALKYL-3-HYDROXY-3-PHENYLAZETIDINE DERIVATIVES USEFUL AS MODULATORS OF CORTICAL CATECHOLAMINERGIC NEUROTRANSMISSION

The present invention relates to novel 3-phenyl-azetidine derivatives, useful for modulating dopamine neurotransmission and extracellular levels of catecholamines, dopamine and norepinephrine, in cerebral cortical areas of the mammalian brain, and more sp

NOVEL 1 -ALKYL- 3 -HYDROXY- 3 -PHENYLAZETIDINE DERIVATIVES USEFUL AS MODULATORS OF CORTICAL CATECHOLAMINERGIC NEUROTRANSMISSION

The present invention relates to novel 3-phenyl-azetidine derivatives, useful for modulating dopamine neurotransmission and extracellular levels of catecholamines, dopamine and norepinephrine, in cerebral cortical areas of the mammalian brain, and more specifically for the treatment of central nervous system disorders. In other aspects the invention relates to pharmaceutical compositions comprising the 3-phenyl-azetidine derivatives of the invention and to the use of these compounds for therapeutic applications. X is OH; R1 is F or Cl; R2 is H, F or Cl; and R3 is n-Pr, i-Pr, n-Bu, i-Bu, s-Bu or t-Bu.