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4-(2-((2-chloro-9-isopropyl-9H-purin-6-yl)aMino)ethyl)phenol, also known as CPI-455, is a purine derivative that functions as a potent and selective inhibitor of the histone methyltransferase enzyme EZH2. This enzyme is integral to gene regulation and is frequently overexpressed in various cancers. CPI-455's unique structure and ability to inhibit EZH2 make it a promising candidate for the development of anticancer therapies.

1227635-07-5

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1227635-07-5 Usage

Uses

Used in Oncology:
CPI-455 is utilized as an anti-cancer agent, specifically targeting the EZH2 enzyme overexpressed in various cancers. By inhibiting EZH2, it has demonstrated significant anti-cancer activity in preclinical studies, making it a potential treatment for lymphoma and other solid tumors.
Used in Pharmaceutical Development:
In the pharmaceutical industry, CPI-455 is used as a candidate for the development of novel anticancer therapies. Its selective inhibition of EZH2 and the resulting impact on gene regulation offer a unique approach to cancer treatment, warranting further research and development to harness its potential in combating cancer.

Check Digit Verification of cas no

The CAS Registry Mumber 1227635-07-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,2,7,6,3 and 5 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1227635-07:
(9*1)+(8*2)+(7*2)+(6*7)+(5*6)+(4*3)+(3*5)+(2*0)+(1*7)=145
145 % 10 = 5
So 1227635-07-5 is a valid CAS Registry Number.

1227635-07-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-(2-((2-Chloro-9-isopropyl-9H-purin-6-yl)amino)ethyl)phenol

1.2 Other means of identification

Product number -
Other names 4-(2-((2-Chloro-9-isopropyl-9H-purin-6-yl)amino)ethyl)phenol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1227635-07-5 SDS

1227635-07-5Upstream product

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