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(R)-α-Methylamino-2,3-dihydro-4-methoxy-7-nitro-γ-oxo-1H-indole-1-butanoic acid, also known as (αR)-2,3-Dihydro-4-methoxy-α-(methylamino)-7-nitro-γ-oxo-1H-Indole-1-butanoic Acid, is a complex organic compound with a unique chemical structure. It is characterized by its indole-based framework, featuring a methylamino group at the α-position, a nitro group at the 7-position, and a γ-oxo-butanoic acid side chain. This molecule is of particular interest due to its potential applications in various fields, particularly in the realm of neuroscience and pharmaceutical research.

1227675-52-6

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1227675-52-6 Usage

Uses

Used in Pharmaceutical Research:
(R)-α-Methylamino-2,3-dihydro-4-methoxy-7-nitro-γ-oxo-1H-indole-1-butanoic acid is used as a ligand for glutamate receptor subtypes. Its application in this field is crucial for the isolation and study of post-synaptic receptor activation, which is a key process in the transmission of nerve impulses and communication between neurons. Understanding the role of MNI-caged-NMDA in receptor activation can lead to the development of new therapeutic strategies for neurological disorders and conditions related to glutamate receptor dysfunction.
Used in Neuroscience Research:
In the field of neuroscience, (R)-α-Methylamino-2,3-dihydro-4-methoxy-7-nitro-γ-oxo-1H-indole-1-butanoic acid serves as a valuable tool for investigating the complex interactions between neurons and their receptors. By acting as a ligand for glutamate receptor subtypes, MNI-caged-NMDA can help researchers gain insights into the molecular mechanisms underlying synaptic transmission and neuronal communication. This knowledge can be instrumental in the development of novel treatments for neurological conditions, such as epilepsy, Alzheimer's disease, and other cognitive disorders.
Used in Drug Development:
The unique properties of (R)-α-Methylamino-2,3-dihydro-4-methoxy-7-nitro-γ-oxo-1H-indole-1-butanoic acid make it a promising candidate for the development of new drugs targeting glutamate receptor subtypes. By modulating the activity of these receptors, MNI-caged-NMDA could potentially be used to treat a range of neurological and psychiatric disorders, including anxiety, depression, and addiction. Furthermore, its ability to influence post-synaptic receptor activation may also make it a valuable asset in the development of drugs aimed at improving cognitive function and memory.

Check Digit Verification of cas no

The CAS Registry Mumber 1227675-52-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,2,7,6,7 and 5 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1227675-52:
(9*1)+(8*2)+(7*2)+(6*7)+(5*6)+(4*7)+(3*5)+(2*5)+(1*2)=166
166 % 10 = 6
So 1227675-52-6 is a valid CAS Registry Number.

1227675-52-6Upstream product

1227675-52-6Downstream Products

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