1227700-50-6 Usage
Uses
The 2-substituted pyridinyl boronic acid has classically been a challenging motif to install, due to instability of the boronic acid. The MIDA Boronate now enables a highly effecient means of installing the 2-pyridyl motif through Suzuki-Miyuara coupling.A General Solution for the 2-Pyridyl Problem
Check Digit Verification of cas no
The CAS Registry Mumber 1227700-50-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,2,7,7,0 and 0 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1227700-50:
(9*1)+(8*2)+(7*2)+(6*7)+(5*7)+(4*0)+(3*0)+(2*5)+(1*0)=126
126 % 10 = 6
So 1227700-50-6 is a valid CAS Registry Number.
1227700-50-6Relevant articles and documents
General method for synthesis of 2-heterocyclic N-methyliminodiacetic acid boronates
Dick, Graham R.,Knapp, David M.,Gillis, Eric P.,Burke, Martin D.
, p. 2314 - 2317 (2010)
A wide range of 2-pyridyl and other difficult-to-access heterocyclic N-methyliminodiacetic acid boronates can be readily prepared from the corresponding bromides via a new method involving direct transligation of 2-heterocyclic trialkoxyborate salts with N-methyliminodiacetic acid (MIDA) at elevated temperatures.
