1227841-32-8

Basic information

• Product Name: (Z)-4-benzylidene-3-propylisoxazol-5(4H)-one
• Synonyms: (Z)-4-benzylidene-3-propylisoxazol-5(4H)-one
• CAS NO: 1227841-32-8
• Molecular Weight: 215.252
• Mol File: 1227841-32-8.mol

Chemical Properties

• CAS DataBase Reference: (Z)-4-benzylidene-3-propylisoxazol-5(4H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-4-benzylidene-3-propylisoxazol-5(4H)-one(1227841-32-8)
• EPA Substance Registry System: (Z)-4-benzylidene-3-propylisoxazol-5(4H)-one(1227841-32-8)

Safety Data

• Hazardous Substances Data: 1227841-32-8(Hazardous Substances Data)

Upstream product

• 1227841-10-2 (E)-benzaldehyde O-3-hex-2-ynoyl oxime 

Relevant articles and documents

Gold-catalyzed cyclization and subsequent arylidene group transfer of O-propioloyl oximes

Gold-catalyzed cyclizations of O-propioloyl oximes via C-N bond formation followed by arylidene group transfer were successfully carried out to afford the corresponding 4-arylideneisoxazol-5(4H)-ones in good to excellent yields. As an example, (E)-benzaldehyde O-3-phenylpropioloyl oxime (1a) was reacted in acetonitrile at 25 °C in the presence of Au(PPh3)NTf2 (5 mol %) to give 4-benzylidene-3-phenylisoxazol-5(4H)-one (2a) in 90% yield. On the basis of crossover experiments, the arylidene "migration" was shown to proceed in an intermolecular manner.