1227870-27-0Relevant articles and documents
Casuarine-6-O-α-d-glucoside and its analogues are tight binding inhibitors of insect and bacterial trehalases
Cardona, Francesca,Goti, Andrea,Parmeggiani, Camilla,Parenti, Paolo,Forcella, Matilde,Fusi, Paola,Cipolla, Laura,Roberts, Shirley M.,Davies, Gideon J.,Gloster, Tracey M.
, p. 2629 - 2631 (2010)
Two novel casuarine-6-α-d-glucoside analogues, as well as the parent compound, were synthesized and tested as inhibitors towards Chironomus riparius, mammalian pig kidney and Escherichia coli trehalases. Their potent and selective activity is promising fo
Synthesis, biological evaluation and docking studies of casuarine analogues: Effects of structural modifications at ring B on inhibitory activity towards glucoamylase
Bonaccini, Claudia,Chioccioli, Matteo,Parmeggiani, Camilla,Cardona, Francesca,Lo Re, Daniele,Soldaini, Gianluca,Vogel, Pierre,Bello, Claudia,Goti, Andrea,Gratteri, Paola
supporting information; experimental part, p. 5574 - 5585 (2011/02/19)
We report the total synthesis of a series of pyrrolizidine analogues of casuarine (1) and their 6-O-α-glucoside derivatives. The synthetic strategy is based on a totally regio- and stereoselective 1,3-dipolar cycloaddition of suitably substitutedalkenes a