1227870-29-2

Upstream product

• 1227870-30-5 methyl (1S,2R,6R,7R,7aR)-6,7-bis(benzyloxy)-5-[(benzyloxy)methyl]-2-hydroxy-3-oxohexahydro-1H-pyrrolizine-1-carboxylate 
• 74808-09-6 2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl trichloroacetimidate 
• 132201-75-3 2,3,4,6-tetra-O-benzyl-D-glucopyranose trichloroacetimidate 

Downstream Products

• 1227870-31-6 (2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl)-(1->6)-O-tris(benzyloxy)-7-deoxy-7-[(hydroxy)methyl]casuarine 

Relevant academic research and scientific papers

Synthesis, biological evaluation and docking studies of casuarine analogues: Effects of structural modifications at ring B on inhibitory activity towards glucoamylase

We report the total synthesis of a series of pyrrolizidine analogues of casuarine (1) and their 6-O-α-glucoside derivatives. The synthetic strategy is based on a totally regio- and stereoselective 1,3-dipolar cycloaddition of suitably substitutedalkenes a

Casuarine-6-O-α-d-glucoside and its analogues are tight binding inhibitors of insect and bacterial trehalases

Two novel casuarine-6-α-d-glucoside analogues, as well as the parent compound, were synthesized and tested as inhibitors towards Chironomus riparius, mammalian pig kidney and Escherichia coli trehalases. Their potent and selective activity is promising fo