1227926-40-0Relevant articles and documents
Facile synthesis of novel pyrimido[1,2-a]pyrimidin-4-ones from highly reactive malonates
Guellue, Mustafa,Dincsoenmezl, Ali,Oezyavas, Oeznur
experimental part, p. 2113 - 2120 (2010/06/15)
A very simple and efficient procedure for the synthesis of novel 2-hydrox.y-4H-pyrimido[1,2-a]pyrimidin-4-ones is described. Title compounds were obtained from the room temperature reaction of 2-aminopyrimidine and its substituted derivatives with bis(2,4,6-trichlorophenyl) malonates. High product yields were observed under optimized conditions. Applicability and reactivity of a range of substituted and unsubstituted phenyl malonates were also investigated. Structural identification of all new compounds was accomplished by spectroscopic methods and elemental analysis.