1227958-64-6Relevant articles and documents
INHIBITORS OF AKT ACTIVITY
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Page/Page column 140, (2010/10/03)
The instant invention provides for substituted fused naphthyridine derivatives that inhibit Akt activity. In particular, the compounds disclosed selectively inhibit one or two of the Akt isoforms. The invention also provides for compositions comprising such inhibitory compounds and methods of inhibiting Akt activity by administering the compound to a patient in need of treatment of cancer.