1228041-08-4Relevant academic research and scientific papers
Preparation, characterization and application of a stationary chromatographic phase from a new (+)-tartaric acid derivative
Legrand, Sacha,Heikkinen, Harri,Nicholls, Ian A.,Root, Andrew,Svenson, Johan,Unelius, C. Rikard
, p. 2258 - 2261 (2010)
The preparation, characterization and application of a new stationary phase derived from 1,4-cyclohexanedione and diethyl (+)-tartrate are described. A suitable TADDOL for immobilization has been synthesized and grafted to a γ-mercaptopropylsilylated silica gel. The resulting modified stationary phase has been characterized and its ability to separate enantiomers has been studied. While the free TADDOL in solution was able to resolve a range of enantiomers, the resolving properties were lost on immobilization. Solid state 13C CPMAS NMR of the new stationary phase was used to explain the lack of stereoselective recognition.
