1228044-57-2Relevant academic research and scientific papers
Design, synthesis, and antibiofilm activity of 2-arylimino-3-aryl-thiazolidine-4-ones
Pan, Bin,Huang, Ren-Zheng,Han, Shi-Qing,Qu, Di,Zhu, Ming-Li,Wei, Ping,Ying, Han-Jie
scheme or table, p. 2461 - 2464 (2010/07/16)
A series of novel 2-arylimino-3-aryl-thiazolidine-4-ones was designed, synthesized and tested for in vitro antibiofilm activity against Staphylococcus epidermidis. Among them tested, some compounds with carboxylic acid groups showed good antibiofilm activity. The antibiofilm concentration of 1x was 6.25 μM. The structure-activity relationships revealed that incorporation of 2-phenylfuran moiety could greatly enhance antibiofilm activity of thiazolidine-4-one.
