1228170-03-3Relevant academic research and scientific papers
Pyrazolone-fused combretastatins and their precursors: synthesis, cytotoxicity, antitubulin activity and molecular modeling studies
Burja, Bojan,?imbora-Zovko, Tamara,Tomi?, Sanja,Jelu?i?, Tihana,Ko?evar, Marijan,Polanc, Slovenko,Osmak, Maja
experimental part, p. 2375 - 2387 (2010/06/19)
A series of pyrazolone-fused combretastatins and precursors were synthesized and their cytotoxicity as well as antitubulin potential was evaluated. The hydrazide 9f and the pyrazolone-fused combretastatins 12a, 12b and 12c were highly cytotoxic against va
