1228183-54-7Relevant academic research and scientific papers
Chemical modification of oximes with N-protected amino acids
Barbakadze, Nana N.,Jones, Rachel A.,Rosario, Nicole Rivera,Nadaraia, Nanuli Sh,Kakhabrishvili, Meri L.,Dennis Hall,Katritzky, Alan R.
, p. 7181 - 7184 (2015/02/19)
The modification of oximes, including 5α-steroids, with N-protected amino acids, in solution phase, using benzotriazole methodology is reported.
Synthesis and antibacterial evaluation of amino acid-antibiotic conjugates
Ibrahim, Mohamed A.,Panda, Siva S.,Birs, Antoinette S.,Serrano, Juan C.,Gonzalez, Claudio F.,Alamry, Khalid A.,Katritzky, Alan R.
, p. 1856 - 1861 (2014/04/17)
Amino acid conjugates of quinolone, metronidazole and sulfadiazine antibiotics were synthesized in good yields using benzotriazole methodology. All the conjugates were screened for their antibacterial activity using methods adapted from the Clinical and L
Green, catalyst-free synthesis of mesalazine conjugates
Ibrahim, Mohamed A.,Panda, Siva S.,Alamry, Khalid A.,Katritzky, Alan R.
, p. 3255 - 3258 (2013/12/04)
A greener protocol for the synthesis of mesalazine conjugates is reported. Mesalazine conjugates are prepared in high yields by a one-pot reaction of mesalazine and aminoacyl/peptidoylbenzotriazoles in water under microwave irradiation. Georg Thieme Verlag Stuttgart New York.
Synthesis and antimalarial bioassay of quinine - peptide conjugates
Panda, Siva S.,Ibrahim, Mohamed A.,Kuecuekbay, Hasan,Meyers, Marvin J.,Sverdrup, Francis M.,El-Feky, Said A.,Katritzky, Alan R.
, p. 361 - 366 (2013/10/08)
Amino acid and peptide conjugates of quinine were synthesized using microwave irradiation in 52-95% yields using benzotriazole methodology. The majority of these conjugates retain in vitro antimalarial activity with IC50 values below 100 nm, similar to quinine.
