1228236-22-3Relevant academic research and scientific papers
Synthesis and evaluation of two series of 4′-aza-carbocyclic nucleosides as adenosine A2A receptor agonists
Beattie, David,Brearley, Andrew,Brown, Zarin,Charlton, Steven J.,Cox, Brian,Fairhurst, Robin A.,Fozard, John R.,Gedeck, Peter,Kirkham, Paul,Meja, Koremu,Nanson, Lana,Neef, James,Oakman, Helen,Spooner, Gillian,Taylor, Roger J.,Turner, Robert J.,West, Ryan,Woodward, Hannah
scheme or table, p. 1219 - 1224 (2010/06/15)
The synthesis of two series of 4′-aza-carbocyclic nucleosides are described in which the 4′-substituent is either a reversed amide, relative to the carboxamide of NECA, or an N-bonded heterocycle. Using established purine substitution patterns, potent and
PURINE DERIVATIVES AS A2A AGONISTS
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Page/Page column 66, (2008/06/13)
Compounds of formula (I):or stereoisomers or pharmaceutically acceptable salts thereof, wherein W, R1,R 2 and R3 have the meanings as indicated in the specification, are useful for treating conditions mediated by activatio
