Basic information

Product Name: Methanol, 1-[3-[5-[2-[[(3R)-1-[(1-Methyl-1H-pyrazol-3-yl)sulfonyl]-3-piperidinyl]aMino]-4-pyriMidinyl]iMidazo[2,1-b]oxazol-6-yl]phenoxy]-, 1-(dihydrogen phosphate)
Synonyms: Methanol, 1-[3-[5-[2-[[(3R)-1-[(1-Methyl-1H-pyrazol-3-yl)sulfonyl]-3-piperidinyl]aMino]-4-pyriMidinyl]iMidazo[2,1-b]oxazol-6-yl]phenoxy]-, 1-(dihydrogen phosphate);GBXJAPBXPROFPY-GOSISDBHSA-N
CAS NO:1228237-47-5
Molecular Formula: C₂₅H₂₇N₈O₈PS
Molecular Weight: 630.569441
EINECS: N/A
Product Categories: N/A
Mol File: 1228237-47-5.mol

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: /
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: Methanol, 1-[3-[5-[2-[[(3R)-1-[(1-Methyl-1H-pyrazol-3-yl)sulfonyl]-3-piperidinyl]aMino]-4-pyriMidinyl]iMidazo[2,1-b]oxazol-6-yl]phenoxy]-, 1-(dihydrogen phosphate)(CAS DataBase Reference)
NIST Chemistry Reference: Methanol, 1-[3-[5-[2-[[(3R)-1-[(1-Methyl-1H-pyrazol-3-yl)sulfonyl]-3-piperidinyl]aMino]-4-pyriMidinyl]iMidazo[2,1-b]oxazol-6-yl]phenoxy]-, 1-(dihydrogen phosphate)(1228237-47-5)
EPA Substance Registry System: Methanol, 1-[3-[5-[2-[[(3R)-1-[(1-Methyl-1H-pyrazol-3-yl)sulfonyl]-3-piperidinyl]aMino]-4-pyriMidinyl]iMidazo[2,1-b]oxazol-6-yl]phenoxy]-, 1-(dihydrogen phosphate)(1228237-47-5)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 1228237-47-5(Hazardous Substances Data)

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1228237-47-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1228237-47-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,2,8,2,3 and 7 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1228237-47:
(9*1)+(8*2)+(7*2)+(6*8)+(5*2)+(4*3)+(3*7)+(2*4)+(1*7)=145
145 % 10 = 5
So 1228237-47-5 is a valid CAS Registry Number.

1228237-47-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name	(3-{5-[2-({(3R)-1-[(1-Methyl-1H-pyrazol-3-yl)sulfonyl]-3-piperidi nyl}amino)-4-pyrimidinyl]imidazo[2,1-b][1,3]oxazol-6-yl}phenoxy)m ethyl dihydrogen phosphate

1.2 Other means of identification

Product number	-
Other names	4-oxidanylidene-6-phenyl-N-(1-phenylethyl)hexanamide

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1228237-47-5 SDS

1228237-47-5Upstream product

1228237-58-8 (R)-di-tert-butyl (3-(5-(2-(1-(1-methyl-1H-pyrazol-3-ylsulfonyl)-piperidin-3-ylamino)pyrimidin-4-yl)imidazo[2,1-b]oxazol-6-yl)phenoxy)methyl phosphate

1228237-47-5Downstream Products

1228237-47-5Relevant academic research and scientific papers

RAF INHIBITORS AND THEIR USES

-

Page/Page column 41-42, (2010/06/20)

The present invention provides imidazooxazole and imidazothiazole compounds and their syntheses. The compounds of the present invention are capable of inhibiting the activity of RAF kinase, such as B-RAF V600E. The compounds are useful for the treatment of cell proliferative disorders such as cancer.

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