1228305-09-6Relevant articles and documents
Discovery of triarylethanolamine inhibitors of the Kv1.5 potassium channel
Beshore, Douglas C.,Liverton, Nigel J.,McIntyre, Charles J.,Claiborne, Christopher F.,Libby, Brian,Culberson, J. Christopher,Salata, Joseph J.,Regan, Christopher P.,Lynch, Joseph J.,Kiss, Laszlo,Spencer, Robert H.,Kane, Stephanie A.,White, Rebecca B.,Yeh, Suzie,Hartman, George D.,Dinsmore, Christopher J.
scheme or table, p. 2493 - 2496 (2010/08/06)
A series of triarylethanolamine inhibitors of the Kv1.5 potassium channel have been prepared and evaluated for their effects in vitro and in vivo. The structure-activity relationship (SAR) studies described herein led to the development of potent, selecti