1228306-41-9Relevant academic research and scientific papers
Catalytic C-H Bond Alkylation of Azoles with Alkyl Halides Mediated by Nickel(II) Complexes of Phenanthridine-Based N^ N-^ N Pincer Ligands
Braun, Jason D.,Herbert, David E.,Mandapati, Pavan,Sidhu, Baldeep K.,Wilson, Gabrielle
, p. 1989 - 1997 (2020)
Ni(II) complexes supported by tridentate N^N-^N diarylamido pincer-type ligands have been demonstrated to act as active catalysts in the carbon-carbon bond forming alkylation of azoles using unactivated alkyl halides. Here, we show that benzann
The nickel/copper-catalyzed direct alkylation of heterocyclic C-H bonds
Vechorkin, Oleg,Proust, Valerie,Hu, Xile
supporting information; experimental part, p. 3061 - 3064 (2010/07/05)
(Figure Presented) Too selective: A general and straightforward protocol for the cross-coupling of non-activated alkyl halides with heterocyclic C-H bonds has been developed. The transformation is chemo- and regioselective and many functional groups on both coupling partners are tolerated. The method employs cheap nickel/copper catalysts, and expands significantly the scope of C-H functionalization (see scheme).
