1228306-60-2Relevant academic research and scientific papers
The nickel/copper-catalyzed direct alkylation of heterocyclic C-H bonds
Vechorkin, Oleg,Proust, Valerie,Hu, Xile
supporting information; experimental part, p. 3061 - 3064 (2010/07/05)
(Figure Presented) Too selective: A general and straightforward protocol for the cross-coupling of non-activated alkyl halides with heterocyclic C-H bonds has been developed. The transformation is chemo- and regioselective and many functional groups on both coupling partners are tolerated. The method employs cheap nickel/copper catalysts, and expands significantly the scope of C-H functionalization (see scheme).
