122833-48-1

Usage

Uses

Used in Pharmaceutical Research:
(S)-1-Phenyl-ethyl-cyanamide is used as a building block in pharmaceutical research for the synthesis of various compounds. Its unique chiral properties allow for the creation of enantiomer-specific drugs, which can have different effects on the body and may lead to more effective treatments.
Used in Organic Synthesis:
In the field of organic synthesis, (S)-PECA is utilized as a key intermediate for the production of a wide range of chemical compounds. Its versatility and reactivity make it a valuable component in the development of new molecules with potential applications in various industries.
Used in Drug Development:
(S)-1-Phenyl-ethyl-cyanamide is used as a potential therapeutic agent in drug development. Its investigation into potential medical applications has shown promise in targeting specific biological pathways, which could lead to the creation of novel drugs with improved efficacy and reduced side effects.
Used in Chemical Research:
(S)-PECA serves as a valuable tool in chemical research, where its unique structural properties and potential biological activities are studied to better understand the underlying mechanisms of various chemical reactions and interactions. This knowledge can be applied to develop new methodologies and techniques in the field of chemistry.

Upstream product

• 25144-91-6 ((S)-1-Phenyl-ethyl)-thiourea 
• 506-68-3 bromocyane 
• 2627-86-3 (S)-1-phenyl-ethylamine 

Downstream Products

• 122833-49-2 Allyl-((S)-1-phenyl-ethyl)-cyanamide 
• 25144-64-3 (S)-(-)-N-α-methylbenzylurea 
• 122833-50-5 1-Allyl-2-ethyl-1-((S)-1-phenyl-ethyl)-isourea 

Relevant academic research and scientific papers

Bromineless bromine as an efficient desulfurizing agent for the preparation of cyanamides and 2-aminothiazoles from dithiocarbamate salts

In a one-pot procedure, bromineless brominating reagent 1,1'-(ethane-1,2-diyl)dipyridinium bistribromide (EDPBT) has been used as a desulfurizing agent in the preparation of organic cyanamides and substituted thiazoles starting from dithiocarbamic acid salts. In this approach, alkyl/aryl isothiocyantes were first obtained by the desulfurization of dithiocarbamic acid salts with EDPBT. The in situ-generated isothiocyanates reacts with an aqueous ammonia, forming alkyl or aryl thioureas, which on subsequent oxidative desulfurization with EDPBT led to the formation of corresponding cyanamides in good yields. Alternatively, an efficient one-pot synthesis of substituted thiazoles has been achieved by the condensation of the in situ-generated 1-aryl thioureas with the in situ-generated -bromoketones from ketones, again using EDPBT. The reagent EDPBT can be easily prepared from the readily available reagents. Desulfurizing ability dominates over its brominating ability for substrates amenable to bromination.

SYNTHESIS OF CHIRAL 1,2-DIAMINES

(1'S,5R,S)-(1'-phenyleth-1'-yl)-5-iodomethyl-imidazolines 4a, b have been synthesised and easily resolved by silica gel chromatography.The correlation between the configuration and the 1H-NMR chemical shifts allows to assign the configuration at the C-5 of these intermediates.Each pure diastereomer has been converted to R(-)- and to S(+)-1,2-propyldiamine, respectively.