122833-54-9Relevant articles and documents
SYNTHESIS OF CHIRAL 1,2-DIAMINES
Bruni, Elena,Cardillo, Giuliana,Orena, Mario,Sandri, Sergio,Tomasini, Claudia
, p. 1679 - 1682 (1989)
(1'S,5R,S)-(1'-phenyleth-1'-yl)-5-iodomethyl-imidazolines 4a, b have been synthesised and easily resolved by silica gel chromatography.The correlation between the configuration and the 1H-NMR chemical shifts allows to assign the configuration at the C-5 of these intermediates.Each pure diastereomer has been converted to R(-)- and to S(+)-1,2-propyldiamine, respectively.