1228343-89-2Relevant academic research and scientific papers
Efficient synthesis of uracil-derived hexa- and tetrahydropyrido[2,3-d] pyrimidines
Tolstoluzhsky, Nikita,Nikolaienko, Pavlo,Gorobets, Nikolay,Van Der Eycken, Erik V.,Kolos, Nadezhda
, p. 5364 - 5369 (2013/09/02)
A reaction of 6-amino-1,3-dimethyluracil with 3-(hetero)aroylacrylic acids and their methyl esters leads to hexahydropyrido[2,3-d]pyrimidine-5-carboxylic acids or the corresponding methyl esters in high to excellent yields. One-pot oxidation of the acid d
