1228344-20-4Relevant academic research and scientific papers
One-pot synthesis of thiazolo[3,4-a]quinoxalines and the related heterocyclic systems using 4-hydroxy-4-alkoxycarbonyl-3,5-diaryl-2- aryliminothia(selena)zolidines as versatile reagents
Mamedov, Vakhid A.,Zhukova, Nataliya A.,Balandina, Alsu A.,Kharlamov, Sergey V.,Beschastnova, Tat'Yana N.,Rizvanov, Il'Dar Kh.,Latypov, Shamil K.
, p. 7363 - 7373 (2012/09/22)
An efficient and versatile one-step method for the synthesis of thiazolo[3,4-a]quinoxalines and related new heterocyclic systems have been developed on the basis of a new strategy for the construction of the pyrazine ring system. The key step of the process involves the cascade annulation of the iminothiazolopyrazine system to benzene in the reaction of 4-hydroxy-3,5-diaryl- 2-phenyliminothiazolidines with 1,2-diaminobenzenes. The use of selenium analogues instead of thiazolidine derivatives in this reaction, leads to selenazolo[3,4-a]quinoxalines and the use of aza analogues instead of 1,2-diaminobenzenes gives aza analogues of thiazolo[3,4-a]quinoxalines.
Fused polycyclic nitrogen-containing heterocycles 20. Thiazolo[3,4-a] quinoxalines from 4-hydroxy-2-phenyliminothiazolidines and C-substituted 1,2-phenylenediamines
Mamedov,Zhukova,Beschastnova,Gubaidullin,Levin,Litvinov
experimental part, p. 191 - 202 (2010/06/12)
The condensation of 4-hydroxy-3,5-diphenyl-2-phenyliminothiazolidine with 4,5-dimethyl-1,2-phenylenediamine affords 7,8-dimethyl-3-phenyl-1- phenyliminothiazolo[3,4-a]quinox-alin-4(5 H)- one; the condensation with 1,2-phenylenediamines containing differen
