122835-14-7Relevant academic research and scientific papers
Efficient one pot synthesis of chromenonaphthyridine derivatives by CuI/InCl3 catalyzed aza diels-alder reaction
Maji, Pradip Kumar,Mahalanobish, Ayan
, p. 42 - 49 (2018)
A mild and efficient method for the synthesis of chromenonaphthyridine derivatives via domino reaction of aminopyridine and different O-propargylated salicylaldehydes using CuI/InCl3 as an efficient catalyst, refluxed in acetonitrile is reported. Mild rea
Synthesis and biological properties of novel 1-methyl-2-(2-(prop-2-yn-1-yloxy)benzylidene) hydrazine analogues
Kivrak, Arif,Yilmaz, Can,Konus, Metin,Koca, Halil,Aydemir, Selahattin,Oagaz, Jeger Ali
, p. 306 - 316 (2018)
1-Methyl-2-(2-(prop-2-yn-1-yloxy)benzylidene)hydrazine analogues were readily prepared in good yields by the reaction of 2-(prop-2-yn-1-yloxy)benzaldehydes and methyl hydrazine. The reaction tolerates a variety of substituents on the 2-hydroxybenzaldehyde
Synthesis of coumarin-sulfonamide derivatives and determination of their cytotoxicity, carbonic anhydrase inhibitory and molecular docking studies
Zengin Kurt, Belma,Sonmez, Fatih,Ozturk, Dilek,Akdemir, Atilla,Angeli, Andrea,Supuran, Claudiu T.
, (2019)
Carbonic anhydrases isoforms CA IX, and XII are known to be highly expressed in various human tissues and malignancies. CA IX is a prominent target for especially colorectal cancers, because it is overexpressed in colorectal cancer and this overexpression
Synthesis of new benzo[f]imidazo[1,2-d][1,4]oxazepines: AgNO3-mediated intramolecular hydroamination
Mahdavi, Mohammad,Hariri, Roshanak,Saeedi, Mina,Foroumadi, Alireza,Shafiee, Abbas,Akbarzadeh, Tahmineh
, p. 7082 - 7084 (2015)
Novel benzo[f]imidazo[1,2-d][1,4]oxazepine derivatives were synthesized from [4,5-diaryl-2-(2-(prop-2-yn-1-yloxy)aryl)-1H-imidazoles] by a AgNO3-promoted 7-exo-dig hydroamination proceeding in DMF at 80 °C.
Efficient synthesis of novel 1, 2, 3-triazole-based diazepam derivatives by click CuAAC reaction: Spectroscopic characterizations and DFT studies
Esmaeeli, Zohreh,Khodabakhshi, Mohammad Reza,Mirjafary, Zohreh,Saeidian, Hamid
, (2021)
A new family of 1, 2, 3-triazole-based benzodiazepines have been synthesized by the Huisgen [3+2] dipolar cycloaddition reaction of diazepam with O-propargyl salicylaldehydes in the aqueous medium. Mild reaction conditions, excellent yields (70–98%), envi
Coumarin-1,2,3-triazole hybrid derivatives: Green synthesis and DFT calculations
Nouraie, Pegah,Moradi Dehaghi, Shahram,Foroumadi, Alireza
, p. 386 - 394 (2019)
A series of new 1,2,3-triazole-coumarin hybrid system are synthesized from the click reaction between 3-azido coumarin and different aromatic terminal alkyne derivatives in a green manner. All compounds are characterized by IR, NMR and UV–VIS spectroscopy
Synthesis and spectral study of a new family of 2,5-diaryltriazoles having restricted rotation of the 5-aryl substituent
Tsyrenova, Biligma,Nenajdenko, Valentine
, (2020)
Efficient synthesis of 2,5-diaryl substituted 4-azido-1,2,3-triazoles by the reaction of sodium azide with dichlorosubstituted diazadienes was demonstrated. The optical properties of the prepared azidotriazoles were studied to reveal a luminescence maximu
Synthesis of Novel 7-methylene-6,7-dihyrobenzo[f]Benzo[4,5]Imidazo[1,2-d][1,4]Oxazepines via Base-mediated Regioselective Intramolecular Hydroamination
Yavari, Hossein,Alinezhad, Heshmatollah,Shafiee, Abbas
, p. 2393 - 2396 (2017)
A versatile and transition metal-free approach for the synthesis of new 7-methylene-6,7-dihyrobenzo[f]benzo[4,5]imidazo[1,2-d][1,4]oxazepines were developed by an efficient 7-exo-dig regioselective hydroamination of 2-(2-(prop-2-yn-1-yloxy)phenyl)-1H-benzo[d]imidazole in the presence of potassium carbonate in DMF at 90°C.
Synthesis and evaluation of novel triazoles and mannich bases functionalized 1,4-dihydropyridine as angiotensin converting enzyme (ACE) inhibitors
Kumbhare, Ravindra M.,Kosurkar, Umesh B.,Bagul, Pankaj K.,Kanwal, Abhinav,Appalanaidu,Dadmal, Tulshiram L.,Banerjee, Sanjay Kumar
, p. 5824 - 5830 (2014)
A series of novel diethyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate embedded triazole and mannich bases were synthesized, and evaluated for their angiotensin converting enzyme (ACE) inhibitory activity. Screening of above synthesized compounds fo
Synthesis, characterization, PASS prediction and in silico ADME studies of ester and ether linked 1,4-disubstituted 1,2,3-triazoles derivatives via click approach
Krishnaswamy,Raghuram Shetty,Roopa,Banu, Salma,Preritha,Rajeshwari,Ravikumar,Pruthviraj,Aruna Kumar,Sreenivasa
, p. 1857 - 1864 (2020)
In the present investigation, we focused our interest on the synthesis of pharmacophoric units (quinoline and 1,2,3-triazole) linked through ester (3a-b) and (substituted aromatic ring and 1,2,3-triazole) linked through an ether (3c-h). The synthesis invo
