122835-71-6Relevant academic research and scientific papers
STUDIES IN VILSMEIER-HAACK REACTION: REACTION OF 3-METHYL-1-PHENYL-4-ARYLIDENE-5-PYRAZOLONE
Awad, Ibrahim M. A.,Hassan, Khairy M.
, p. 706 - 712 (2007/10/02)
The 3-methyl group in Ia, b has been found to undergo diformylation by Vilsmeier reagent to give the aminoacrolein derivatives (IIa, b).Treatment of IIa, b with different reagents affords the related 1-phenyl-4-arylidene-5-pyrazolone derivatives with different heterocyclic systems in the 3-position.The Vilsmeier reaction on pyrazolopyrazole (XIII) have been utilized to prove chemically that new heterocyclic system are formed only at the 3-position and no addition on the carbon-carbon double bond in the conjugated system O=C-C=C-(B) takes place.
