1228358-99-3Relevant academic research and scientific papers
Method for preparing 2, 6-disubstituted aryl borate compounds
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Paragraph 0027-0032, (2021/02/19)
The invention relates to a method for preparing 2, 6-disubstituted aryl borate compounds, which comprises the following steps: adding a palladium catalyst and a phosphine ligand into a reaction tube,adding norbornene, adding a first inorganic base and a second inorganic base, adding alcohols, adding an organic solvent, replacing the system with inert gas for protection, heating, carrying out constant-temperature reaction, and separating and purifying to obtain the 2, 6-disubstituted aryl borate compounds. The synthesis method disclosed by the invention has the characteristics of cheap and easily available raw materials, mild reaction conditions, good substrate adaptability, simple operation, stable product quality, high purity and the like. The series of 2, 6-disubstituted aryl borate products synthesized by the method have wide application value as organic synthesis intermediates.
Ambient-temperature cobalt-catalyzed cycloaddition strategies to aromatic boronic esters
Auvinet, Anne-Laure,Harrity, Joseph P. A.,Hilt, Gerhard
supporting information; experimental part, p. 3893 - 3896 (2010/08/06)
Figure presented The room-temperature cobalt-catalyzed [4 + 2] cycloaddition of alkynylboronates and 1,3-dienes provides a convenient and general method for the synthesis of benzene-based aromatic boronic esters. Two complementary aromatization strategies involving in situ elimination and DDQ oxidation were explored, with the latter finding more generality. Finally, the potential of this technique to generate highly functionalized biaryls has been demonstrated via the synthesis of chiral (racemic) DMAP catalysts.
