1228443-30-8Relevant articles and documents
Novel chemoenzymatic methodology for the regioselective glycine loading on polyhydroxy compounds
Malhotra, Shashwat,Calderon, Marcelo,Prasad, Ashok K.,Parmar, Virinder S.,Haag, Rainer
, p. 2228 - 2237 (2010)
In the present work, we have developed a highly efficient temperature-dependent chemo-enzymatic methodology for the regioselective synthesis of novel esters of glycerol, G1 tri-glycerol dendrons and related esters for the first time using 4-nitrophenyl 2-(tert-butoxycarbonyl)acetate (Boc-gly-Ph-pNO2) (2) as the acylating agent. This methodology offers efficient and controlled loading of amino acid (glycine) on polyhydroxy compounds.