1228504-87-7Relevant academic research and scientific papers
Copper(i)-amine metallo-organocatalyzed synthesis of carbo- and heterocyclic systems
Montaignac, Benjamin,Oestlund, Victor,Vitale, Maxime R.,Ratovelomanana-Vidal, Virgnie,Michelet, Veronique
supporting information; experimental part, p. 2300 - 2306 (2012/04/10)
The efficient and atom economical synthesis of 5-membered cyclic structures has been achieved through the combination of amino catalysis and metal catalysis. The discovery of a novel metallo-organocatalytic system merging the use of a catalytic copper(i)
InCl3/CyNH2 cocatalyzed carbocyclization reaction: An entry to α-disubstituted exo -methylene cyclopentanes
Montaignac, Benjamin,Vitale, Maxime R.,Ratovelomanana-Vidal, Virginie,Michelet, Veronique
supporting information; experimental part, p. 8322 - 8325 (2011/02/28)
An efficient and cheap synthetic approach to functionalized exo-methylene cyclopentanes has been developed from α-disubstituted formyl-alkynes by merging amine catalysis with the indium activation of alkynes. We uncovered the crucial role of the amine cocatalyst and the development of a new cooperative catalytic system allowed the cyclization of a broad range of substrates. A mechanistic study was realized in order to rationalize the determining influence of the amine cocatalyst.
Combined InCl3- and amine-catalyzed intramolecular addition of α-disubstituted aldehydes onto unactivated alkynes
Montaignac, Benjamin,Vitale, Maxime R.,Michelet, Veronique,Ratovelomanana-Vidal, Virginie
supporting information; experimental part, p. 2582 - 2585 (2010/08/04)
The combination of enamine-type catalysis to the indium-catalyzed activation of alkynes allows the efficient preparation of functionalized cyclopentanes bearing a quaternary stereogenic center. A broad range of formylalkynyl derivatives has been prepared.
