1228532-17-9Relevant academic research and scientific papers
Synthesis of water-soluble phosphinophenol for traceless staudinger ligation
Weisbrod, Samuel H.,Marx, Andreas
, p. 787 - 789 (2010)
The traceless Staudinger ligation can be mediated in water without organic co-solvents if charged groups render the phenylphosphine reagent water soluble. Here the synthesis of a new water-soluble phosphine is presented based on a diphenylphosphino-phenol reagent. Staudinger ligation with this reagent and azido glycine amide showed conversion of 77%.
