1228548-44-4 Usage
Chemical composition
Consists of a naphthalene ring with an amine group and a chlorine atom attached to it.
Chirality
A chiral compound with (1S)designation indicating the stereochemistry of the molecule.
Use in synthesis
Often used as a building block in organic synthesis for the production of pharmaceuticals and agrochemicals.
Medicinal applications
Studied for potential use in medicinal applications, particularly in the development of new therapeutic agents.
Handling precautions
Should be handled with care and in accordance with safety protocols due to potential hazards to human health and the environment.
Check Digit Verification of cas no
The CAS Registry Mumber 1228548-44-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,2,8,5,4 and 8 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1228548-44:
(9*1)+(8*2)+(7*2)+(6*8)+(5*5)+(4*4)+(3*8)+(2*4)+(1*4)=164
164 % 10 = 4
So 1228548-44-4 is a valid CAS Registry Number.
1228548-44-4Relevant articles and documents
Synthesis method of levo-amino compound
-
Paragraph 0008; 0012, (2017/10/12)
The invention discloses a synthesis method of a levo-amino compound S-7-chloro-1,2,3,4-tetrahydronaphthalene-1-amine. The method includes the steps of: performing a reaction to a raw material, 7-chloro-1-tetralone, with hydroxylamine to generate oxime; performing hydrogenation reduction to the oxime to prepare racemized amine; performing a one-pot dynamic kinetic resolution reaction to the product amine with lipase, a racemization catalyst and an acyl group donor; and hydrolyzing a resolution reaction product to prepare the S-7-chloro-1,2,3,4-tetrahydronaphthalene-1-amine. The method has simple operations, high product yield, high optical purity of the resolution product, and the like.
