1228552-29-1

Basic information

• Product Name: 3-(Diaminomethylene)furan-2,4(3H,5H)-dione hydrochloride
• Synonyms: 3-(Diaminomethylene)furan-2,4(3H,5H)-dione hydrochloride;3-(diaminomethylidene)oxolane-2,4-dione
• CAS NO: 1228552-29-1
• Molecular Formula: C5H6N2O3
• Molecular Weight: 142.11274
• Mol File: 1228552-29-1.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 319.8±42.0 °C(Predicted)
• Appearance: /
• Density: 1.597±0.06 g/cm3(Predicted)
• PKA: 3.00±0.20(Predicted)
• CAS DataBase Reference: 3-(Diaminomethylene)furan-2,4(3H,5H)-dione hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(Diaminomethylene)furan-2,4(3H,5H)-dione hydrochloride(1228552-29-1)
• EPA Substance Registry System: 3-(Diaminomethylene)furan-2,4(3H,5H)-dione hydrochloride(1228552-29-1)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 1228552-29-1(Hazardous Substances Data)

Relevant articles and documents

Synthesis of diaminomethylidene derivatives of tetronic acid

Methyl 4-chloro-3-oxobutanoate reacts with benzoylcyanamide in the presence of catalytic amounts of Ni(acac)2 to give the corresponding ketene N-benzoylaminal, which is transformed in boiling AcOH into 3-[(amino) (benzoylamino)methylidene]tetrahydrofuran-2,4-dione. Debenzoylation of the latter in the presence of EtONa in EtOH yields a N,N-unsubstituted diaminomethylidene derivative of tetronic acid. Cyclization of the adduct of methyl 4-chloro-3-oxobutanoate with benzoylcyanamide in the presence of triethylamine follows a different pathway leading to methyl 2-amino-1-benzoyl-4- oxo-4,5-dihydro-1H-pyrrole-3-carboxylate.