1228566-94-6

Basic information

• Product Name: (S)-tert-butyl 6-oxopiperidin-3-ylcarbamate
• Synonyms: (S)-tert-butyl 6-oxopiperidin-3-ylcarbamate;Carbamic acid, N-[(3R)-6-oxo-3-piperidinyl]-, 1,1-dimethylethyl ester
• CAS NO: 1228566-94-6
• Molecular Formula: C10H18N2O3
• Molecular Weight: 214.26152
• Mol File: 1228566-94-6.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: (S)-tert-butyl 6-oxopiperidin-3-ylcarbamate(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-tert-butyl 6-oxopiperidin-3-ylcarbamate(1228566-94-6)
• EPA Substance Registry System: (S)-tert-butyl 6-oxopiperidin-3-ylcarbamate(1228566-94-6)

Safety Data

• Hazardous Substances Data: 1228566-94-6(Hazardous Substances Data)

Usage

General Description

(S)-tert-butyl 6-oxopiperidin-3-ylcarbamate is a chemical compound with the molecular formula C11H20N2O3. It is a carbamate derivative of piperidine that contains a tert-butyl group attached to the nitrogen atom. (S)-tert-butyl 6-oxopiperidin-3-ylcarbamate is commonly used in organic synthesis and medicinal chemistry as a building block for the synthesis of various pharmaceutical and biologically active molecules. Its unique structure and properties make it a valuable intermediate in the production of drugs and other organic compounds. Additionally, (S)-tert-butyl 6-oxopiperidin-3-ylcarbamate has potential applications in the development of new therapeutic agents for various medical conditions.

Upstream product

• 91229-98-0 1-(benzyloxy)-5-<(tert-butyloxycarbonyl)amino>-piperidone 
• 45214-91-3 (2S)-2-[(tert-butoxy)carbonylamino]-4-(methoxycarbonyl)butanoic acid 
• 130223-39-1 methyl 4-<(tert-butyloxycarbonyl)amino>-5-(O-tosyl)pentanoate 
• 330680-83-6 methyl (4S)-5-azido-4-[(tert-butoxycarbonyl)amino]pentanoate 
• 251987-13-0 (4S)-N-benzyloxy-4-(N-tert-butoxycarbonyl)amino-5-[(1-ethoxy)ethoxy]pentanamide 
• 251987-04-9 (5S)-1-tert-butoxycarbonyl-5-(1-ethoxy)ethoxymethyl pyrrolidin-2-one 
• 91229-96-8 (4S)-N-benzyloxy-4-(N-tert-butoxycarbonyl)amino-5-hydroxypentanamide 
• 672883-28-2 4-tert-butoxycarbonylamino-5-methanesulfonyloxy-pentanoic acid methyl ester 
• 126587-35-7 methyl (4S)-4-[(tert-butoxy)carbonylamino]-5-hydroxypentanoate 
• 515863-25-9 (S)-tert-butyl 2-(azidomethyl)-5-oxopyrrolidine-1-carboxylate 
• 93288-20-1 [(2S)-5-oxopyrrolidin-2-yl]methyl methanesulfonate 
• 17342-08-4 (S)-Pyroglutaminol 
• 24424-99-5 di-tert-butyl dicarbonate 

Downstream Products

• 1527525-47-8 tert-butyl N-[(3S)-1-[3-methyl-6-[6-(6-methylpyrazin-2-yl)pyrazolo[4,3-c]pyridin-1-yl]-2-pyridyl]-6-oxo-3-piperidyl]carbamate 
• 1527523-89-2 (5S)-5-amino-1-[3-methyl-6-[6-(6-methylpyrazin-2-yl)pyrazolo[4,3-c]pyridin-1-yl]-2-pyridyl]piperidin-2-one 
• 1527525-46-7 tert-butyl N-[(3S)-1-(6-chloro-3-methyl-2-pyridyl)-6-oxo-3-piperidyl]carbamate 

Relevant articles and documents

Synthesis of chiral n,n+1-diamino acids and their application to the construction of dendrimers

Efficient methods for the synthesis of chiral n,n+1-diamino acids starting from L-glutamic acid were developed. A second generation prototype amino acid based dendrimer, containing 1,3-propanediamine as the core and 4,5-diaminopentanoic acid as the branching unit, was synthesised following the divergent approach. Diaminobutane poly(propyleneimine) dendrimers modified at the periphery with n,n+1-diamino acids were synthesized and characterized.

Synthesis of 5-amino- and 4-hydroxy-2-phenylsulfonylmethylpiperidines

Suitable protected 5-amino- and 4-hydroxy-2-phenylsulfonylmethylpiperidines were synthesized from functionalized N-benzyloxycarbonylpiperidin-l-ones through the opening of lactam ring by methyl phenyl sulfone carbanion followed by reductive aminocyclization.

Diastereoselective synthesis of enantiopure differentially protected cis-4,5-diaminopiperidin-2-one through intramolecular transamidation

The diastereoselective synthesis of enantiopure differentially protected cis-4,5-diaminopiperidin-2-one was achieved by means of conjugate addition of ammonia to an unsaturated γ-lactam and transamidation reaction with ring expansion as the main steps.