1228570-45-3 Usage
General Description
(S)-3-AMINO-3-(3-TRIFLUOROMETHYL-PHENYL)-PROPIONIC ACID METHYL ESTER is a compound with the chemical formula C11H12F3NO2. It is commonly used in organic synthesis and medicinal chemistry as a building block for the preparation of various pharmaceuticals and agrochemicals. This chemical is a methyl ester derivative of (S)-3-aminocarboxyphenyl, which indicates its potential use as a chiral intermediate in the synthesis of pharmaceutical compounds. The trifluoromethyl group on the phenyl ring enhances the lipophilicity and metabolic stability of the compound, making it an attractive candidate for drug development and research applications.
Check Digit Verification of cas no
The CAS Registry Mumber 1228570-45-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,2,8,5,7 and 0 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1228570-45:
(9*1)+(8*2)+(7*2)+(6*8)+(5*5)+(4*7)+(3*0)+(2*4)+(1*5)=153
153 % 10 = 3
So 1228570-45-3 is a valid CAS Registry Number.
1228570-45-3Relevant articles and documents
Microwave Assisted Synthesis of Trifluoro Substituted 2-Aminobenzimidazole Derivatives via Iodoacetic Acid Mediated One-pot Condensation
Sriram,Sapthagiri,Ilavarasan,Ravi
, p. 2440 - 2446 (2017)
Microwave-assisted efficient one-pot syntheses of trifluoro substituted 2-aminobenzimidazole derivative were synthesized using iodoacetic acid mediated cyclodesulfurization of thioureas. This method eliminates need to handle preformed substituted thioureas, requires lesser reaction time and temperature, is facile, and also gives higher yields of the target molecules.