1228660-93-2Relevant academic research and scientific papers
Regioselective Functionalization of Chlorophthalazine Derivatives
Crestey, Francois,Knochel, Paul
, p. 1097 - 1106 (2010)
Chlorophthalazines were efficiently metalated using tmpZnClLiCl under microwave irradiation. This provided novel substituted phthalazine derivatives after subsequent trapping of the resulting organometallic reagents with various electrophiles. Moreover, Negishi cross-coupling reactions have been performed affording new polyfunctionalized phthalazine scaffolds in very good yields.
