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1228668-06-1

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1228668-06-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1228668-06-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,2,8,6,6 and 8 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1228668-06:
(9*1)+(8*2)+(7*2)+(6*8)+(5*6)+(4*6)+(3*8)+(2*0)+(1*6)=171
171 % 10 = 1
So 1228668-06-1 is a valid CAS Registry Number.

1228668-06-1Downstream Products

1228668-06-1Relevant articles and documents

Discovery of functionalized bisimidazoles bearing cyclic aliphatic-phenyl motifs as HCV NS5A inhibitors

Zhong, Min,Peng, Eric,Huang, Ningwu,Huang, Qi,Huq, Anja,Lau, Meiyen,Colonno, Richard,Li, Leping

, p. 5731 - 5737 (2015/01/08)

This Letter describes the discovery of a number of functionalized bisimidazoles bearing a cyclohexylphenyl, piperidylphenyl, or bicyclo[2,2,2]octylphenyl motif as HCV NS5A inhibitors. Compounds 2c, 4b and 6 have demonstrated low single-digit nM potency in gt-1a replicon and double-digit pM potency in gt-1b replicon, respectively. Moreover, both 4b and 6 have, respectively, exhibited good oral bioavailability in rats with a favorable liver/plasma ratio of the drug concentration.

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