1228675-66-8Relevant articles and documents
Polyketide assembly by alkene-alkyne reductive cross-coupling: Spiroketals through the union of homoallylic alcohols
Canterbury, Daniel P.,Micalizio, Glenn C.
supporting information; experimental part, p. 7602 - 7604 (2010/07/08)
A reaction sequence composed of regioselective formal hydroalkynylation, reductive ene-yne cross-coupling, and oxidative cyclization has been developed to prepare stereochemically dense spiroketals. Overall, the chemistry defines a three-component coupling process for the union of two homoallylic alcohol-based substrates with trimethylsilylacetylene.